ppOrganisation/Company IDIBELL Research Field Biological sciences » Biology Researcher Profile Recognised Researcher (R2) Positions Postdoc Positions Application Deadline 5 Aug 2026 - 12:30 (Europe/Madrid) Country Spain Type of Contract To be defined Job Status Full-time Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No /p h3Offer Description /h3 pThe Laboratory of Cancer Metabolism is looking for a highly motivated bpostdoctoral candidate /bwilling to participate to the next call of Marie Curie Postdoctoral Fellowship and other mobility fellowship programs (EMBO LTF, Human Frontiers HFSP etc.). /p pThe group focuses on understanding bhow the process of oncogenic transformation reprograms the translatome /b, particularly (1) how metabolic changes alter the repertoire of translated mRNAs and (2) how cancer cells can exploit such translational networks to survive and overcome standard chemotherapeutic regimens in colorectal cancer and other MYC-driven tumors. /p pWe have identified a specialized subset of b40S ribosomes /b, which in a complex with the RNA binding protein bLARP1 /b, bind and preserve a discrete population of mRNAs, termed b5’TOPs /b, which not only include Ribosomal Proteins (RPs) and translational factors, but also a new set of anabolic mRNAs (Gentilella et al., Molecular Cell 17),



which can be translationally switched ON and OFF depending on the cellular metabolic state (Fuentes et al, Science Advances 21; Morcelle et al, Cancer Res 19, Fuentes et al., NAR Cancer 2024). This mechanism plays a major role in bMYC-driven oncogenesis /b, preparing the anabolic potential of transformed cellsin a poised state and connecting it with the metabolic sensing pathway governed by mTOR (Fuentes et al., PNAS 2026). /p pThe long term goal of the lab is to understand by a multi-disciplinary approach cellular adaptations sustaining the bbiomass production /b in tumor contexts, and to identify bmetabolic /b bvulnerabilities /bthat could constitute critical targets in cancer treatment. /p pThe search is primarily targeted atbscientists who have recently graduated /b in any of the fields related to molecular biology, biochemistry and cell biology with a competitive CV to sustain the application.The project requires solid expertise in molecular and cellular biology. Previous experience with translational analysis will be highly valued. The candidate should possess strong written and verbal communication skills. /p pThe Laboratory of Cancer Metabolism is located inside the IDIBELL, a research center that integrates the biomedical research of the Bellvitge University Hospital (HUB), the Catalan Institute of Oncology (ICO), and the University of Barcelona in the Bellvitge Campus (UB) and the Viladecans Hospital (HV), located in south Barcelona. /p /p #J-18808-Ljbffr

📌 Postdoctoral candidate in Cancer Metabolism (MSCA applicant) (España)
🏢 Idibell
📍 España