TakeTalent joins PharmaMar i n the search for a Clinical Pharmacology Scientist to support the development of innovative oncology therapies through cutting-edge clinical pharmacology and model-informed drug development strategies .

Descubra si esta posibilidad es adecuada para usted leyendo toda la información que sigue a continuación.

At PharmaMar , they are committed to advancing science and transforming patient outcomes through innovative oncology research. The Clinical Pharmacology team plays a critical role in early clinical development, generating the pharmacokinetic, pharmacodynamic and translational insights needed to optimize drug development and support regulatory decision-making.

Support the implementation of Clinical Pharmacology and Early Clinical Development plans with scientific rigor and a high level of autonomy.

- Provide guidance and scientific mentorship to Clinical Pharmacology Scientists and Associate Scientists within the team.
- Coordinate and oversee bioanalytical activities, including sample shipment tracking, vendor management, review of validation plans, budgets and work orders.
- Perform pharmacokinetic analyses, including Non-Compartmental Analysis (NCA), Population Pharmacokinetic (PopPK) analysis and Physiologically Based Pharmacokinetic (PBPK) modeling.
- Conduct pharmacodynamic and PK/PD analyses to assess treatment efficacy, dose-limiting toxicities and exposure-response relationships.
- Support first-in-human (FIH) studies, including ECG/Holter monitoring activities and c-QT/t-QT analyses.
- Contribute to Model-Informed Drug Development (MIDD) initiatives through pharmacometric analyses, simulations and interpretation of results.
- Develop and maintain high-quality analytical workflows and databases following Good Coding Practices.
- Contribute to Clinical Pharmacology sections of study protocols, development plans,



scientific publications and technical reports.
- Provide scientific support to Regulatory Affairs activities and interactions with agencies such as the EMA and FDA.
- Collaborate closely with cross-functional teams including Medical Oncology, Biostatistics, Data Management and other key stakeholders.
- Participate in departmental initiatives that contribute to the overall success of Early Clinical Development programs.

Bachelor's degree in Pharmacy, Medicine, Biology, Biotechnology or a related scientific discipline.

- Master's degree and PhD in Pharmacology , Immunology, Computational Biology, Bioinformatics, Biostatistics or a related field.
- Fluent English, both written and spoken.
- More than 3 years of experience in clinical research, preferably within pharmacology, immunology or translational medicine.
- Strong programming skills in R and SAS for data analysis and process automation.
- Knowledge of additional programming languages such as Python and Bash.
- Solid understanding of statistical methodologies, including descriptive, univariate and multivariate analyses.
- Experience with Next-Generation Sequencing (NGS), pharmacogenetics, genotyping analyses and bioinformatics pipelines.
- Competitive annual salary and performance-based bonus.
- Comprehensive benefits package, including private health insurance, employee share plan, company canteen, continuous training and development opportunities, among others.
- Hybrid working model available after successfully completing the six-month probation period, combining on-site collaboration with remote work flexibility. xqbhyrx
- The opportunity to contribute to groundbreaking oncology research in an innovative and science-driven environment.
- If you are passionate about clinical pharmacology, translational science and innovative drug development, we would love to hear from you.

📌 Clinical Pharmacology Principal Scientist (Madrid)
🏢 BUSINESS SOLUTIONS by TakeTalent
📍 Madrid