JOB DESCRIPTIONWe are looking for a Senior Research Technician to take ownership of a high-impact project on non-genetic drug resistance in melanoma—and we want someone who treats this as their own scientific mission. Your core task: develop and implement a physiologically relevant 3D model that captures the real-time crosstalk between tumor cells and the microenvironment, directly informing combination strategies to overcome treatment failure. We need a hands-on expert in primary cell culture, multiplex assays, and 3D scaffolds someone who troubleshoots independently, mentors effectively, and bridges lab work with translational goals.MAIN RESPONSIBILITIES- Establish and optimize a 3D co-culture model integrating melanoma cells with stromal/immune components to mimic the tumor microenvironment.- Perform drug sensitivity assays and longitudinal viability tests to monitor treatment response and acquired resistance.- Conduct molecular analyses (RNA/protein extraction, qPCR, Western blotting, cytokine profiling) to characterize non-genetic adaptive changes.- Carry out high-content imaging and quantitative microscopy to assess spatial interactions, invasion, and phenotypic plasticity within 3D constructs.- Maintain detailed electronic lab records, analyze data with statistical rigor, and present results in team meetings.- Train and supervise junior technicians/students, manage reagent inventory, and troubleshoot protocols proactively.- Collaborate with bioinformaticians to integrate wet-lab data with omics datasets, feeding results into therapeutic strategy development.QUALIFICATIONS AND EXPERIENCIE- Master in Biomedicine or closely related field,



with a focus on cancer research.- Experience in tissue culture and data analysis- Strong experience in molecular and cellular biology techniques (DNA and RNA isolation, RNA quantification, qPCR and immunofluoresence).- Strong experience in cell culture, including the establishment of primary cultures.- Experience in proteomics, particularly in O-Link analysis.- Hands-on experience in clinical research environments.- Basic knowledge of Rstudio.- Good command of English, both written and spoken.- International experience will be considered an asset.- Experience in sòlid tumors tumors will be considered an asset.- Proactive, motivated, and responsible individual with strong organizational skills and the ability to work autonomouslyWHAT WE OFFER- Indefinite contract (Science Law 14/2011) Full-time contract- 20.000-25.000 gross salary- Incorporation date: 1st of September- Gross annual remuneration inherent to the square objected to this call, will be fixed based on the experience provided and the skills of the candidate, distributed in 12 payments.- Adaptable payment (childminding vouchers and meal voucher).- 23 days holiday and 5 days for personal matters.- Training capsules by the company.- Be part of an excellent multidisciplinary research centre with the HRS4R badge.- Location on the Can Ruti Campus, a first-class translational research environment in the Barcelona area, in a very stimulating scientific environment. The IGTP offers a supportive, friendly and collaborative ecosystem to promote professional development and help you achieve your research goals.FOR MORE INFORMATIONhttps://www.Germanstrias.Org/en/research/cancer/23/oncology-translational-research-otrDEADLINE FOR APPLICATIONSThe call for applications will close on August 10th, 2026.#J-18808-Ljbffr

📌 2026_112_senior Research Technician (Badalona)
🏢 IGTP Retreat
📍 Badalona