TakeTalent joins PharmaMar in the search for a Clinical Pharmacology Scientist to support the development of innovative oncology therapies through cutting-edge clinical pharmacology and model-informed drug development strategies.

Se anima a todos los posibles solicitantes a que se desplacen y lean la descripción completa del puesto antes de presentar su candidatura.

At PharmaMar, they are committed to advancing science and transforming patient outcomes through innovative oncology research.

The Clinical

Pharmacology team plays a critical role in early clinical development, generating the pharmacokinetic, pharmacodynamic and translational insights needed to optimize drug development and support regulatory decision-making.

Support the implementation of Clinical Pharmacology and Early Clinical Development plans with scientific rigor and a high level of autonomy.

- Provide guidance and scientific mentorship to Clinical Pharmacology Scientists and Associate Scientists within the team.
- Coordinate and oversee bioanalytical activities, including sample shipment tracking, vendor management, review of validation plans, budgets and work orders.
- Perform pharmacokinetic analyses, including Non-Compartmental Analysis (NCA), Population Pharmacokinetic (PopPK) analysis and Physiologically Based Pharmacokinetic (PBPK) modeling.
- Conduct pharmacodynamic and PK/PD analyses to assess treatment efficacy, dose-limiting toxicities and exposure-response relationships.
- Support first-in-human (FIH) studies, including ECG/Holter monitoring activities and c-QT/t-QT analyses.
- Contribute to Model-Informed Drug Development (MIDD) initiatives through pharmacometric analyses, simulations and interpretation of results.




- Develop and maintain high-quality analytical workflows and databases following Good Coding Practices.
- Contribute to Clinical Pharmacology sections of study protocols, development plans, scientific publications and technical reports.
- Collaborate closely with cross-functional teams including Medical Oncology, Biostatistics, Data Management and other key stakeholders.
- Bachelor's degree in Pharmacy, Medicine, Biology, Biotechnology or a related scientific discipline.
- Master's degree and PhD in Pharmacology, Immunology, Computational Biology, Bioinformatics, Biostatistics or a related field.
- Fluent English, both written and spoken.
- More than 3 years of experience in clinical research, preferably within pharmacology, immunology or translational medicine.
- Strong programming skills in R and SAS for data analysis and process automation.
- Knowledge of additional programming languages such as Python and Bash.
- Solid understanding of statistical methodologies, including descriptive, univariate and multivariate analyses.
- Experience with Next-Generation Sequencing (NGS), pharmacogenetics, genotyping analyses and bioinformatics pipelines.
- Competitive annual salary and performance-based bonus.
- Comprehensive benefits package, including private health insurance, employee share plan, company canteen, continuous training and development opportunities, among others.
- Hybrid working model available after successfully completing the six-month probation period, combining on-site collaboration with remote work flexibility. xugodme
- The opportunity to contribute to groundbreaking oncology research in an innovative and science-driven environment. If you are passionate about clinical pharmacology, translational science and innovative drug development, we would love to hear from you.

📌 Clinical Pharmacology Principal Scientist (Madrid)
🏢 BUSINESS SOLUTIONS by TakeTalent
📍 Madrid