pstrongTakeTalent /strongjoins strongPharmaMar i /strongn the search for a strongClinical Pharmacology Scientist /strongto support the development of innovative oncology therapies through cutting-edge strongclinical pharmacology /strongand strongmodel-informed drug development strategies /strong.

Por favor, lea detenidamente la información de esta oferta de empleo para entender exactamente qué se espera de los posibles candidatos.

/ppbr/ppAt strongPharmaMar /strong, they are committed to advancing science and transforming patient outcomes through innovative oncology research.

The Clinical Pharmacology team plays a critical role in early clinical development, generating the pharmacokinetic, pharmacodynamic and translational insights needed to optimize drug development and support regulatory decision-making.

/ppbr/ppstrongWhat will you do? /strong /ppbr/pp• Support the implementation of Clinical Pharmacology and Early Clinical Development plans with scientific rigor and a high level of autonomy.

/pp• Provide guidance and scientific mentorship to Clinical Pharmacology Scientists and Associate Scientists within the team.

/pp• Coordinate and oversee bioanalytical activities, including sample shipment tracking, vendor management, review of validation plans, budgets and work orders.

/pp• Perform pharmacokinetic analyses, including Non-Compartmental Analysis (NCA), Population Pharmacokinetic (PopPK) analysis and Physiologically Based Pharmacokinetic (PBPK) modeling.

/pp• Conduct pharmacodynamic and PK/PD analyses to assess treatment efficacy, dose-limiting toxicities and exposure-response relationships.

/pp• Support first-in-human (FIH) studies, including ECG/Holter monitoring activities and c-QT/t-QT analyses.





/pp• Contribute to Model-Informed Drug Development (MIDD) initiatives through pharmacometric analyses, simulations and interpretation of results.

/pp• Develop and maintain high-quality analytical workflows and databases following Good Coding Practices.

/pp• Contribute to Clinical Pharmacology sections of study protocols, development plans, scientific publications and technical reports.

/pp• Provide scientific support to Regulatory Affairs activities and interactions with agencies such as the EMA and FDA.

/pp• Collaborate closely with cross-functional teams including Medical Oncology, Biostatistics, Data Management and other key stakeholders.

/pp• Participate in departmental initiatives that contribute to the overall success of Early Clinical Development programs.

/ppbr/ppstrongPosition requirements /strong /ppbr/pp• Bachelor’s degree in strongPharmacy, Medicine, Biology, Biotechnology /strong or a related scientific discipline.

/pp• Master’s degree and PhD in strongPharmacology /strong, Immunology, Computational Biology, Bioinformatics, Biostatistics or a related field.

/pp• Fluent English, both written and spoken.

/pp• More than 3 years of experience in clinical research, preferably within pharmacology, immunology or translational medicine.

/pp• Experience authoring scientific publications and technical reports.





/pp• Proven expertise in pharmacometric modeling tools such as strongNONMEM, Monolix, PK-Sim or similar platforms.

/strong /pp• Strong programming skills in R and SAS for data analysis and process automation.

/pp• Knowledge of additional programming languages such as Python and Bash.

/pp• Experience in bioanalysis and biomarker evaluation.

/pp• Solid understanding of statistical methodologies, including descriptive, univariate and multivariate analyses.

/pp• Experience withstrong Next-Generation Sequencing /strong(NGS), pharmacogenetics, genotyping analyses and bioinformatics pipelines.

/pp• Excellent communication skills and the ability to work independently while contributing effectively within multidisciplinary teams.

/ppbr/ppstrongWhat do we offer? /strong /ppbr/pp• Competitive annual salary and performance-based bonus.

/pp• Comprehensive benefits package, including private health insurance, employee share plan, company canteen, continuous training and development opportunities, among others.

/pp• Adaptable start time (7:30h to 9:30h) and intensive working hours on Fridays.

/pp• Hybrid working model available after successfully completing the six-month probation period, combining on-site collaboration with remote work flexibility.

/pp• The opportunity to contribute to groundbreaking oncology research in an innovative and science-driven environment. xugodme

/pp• A strong commitment to diversity, equal opportunities and an inclusive work environment where all talent is valued and respected.

/ppbr/ppstrongIf you are passionate about clinical pharmacology, translational science and innovative drug development, we would love to hear from you.

/strong /p

📌 Clinical Pharmacology Principal Scientist (Madrid)
🏢 CareerWallet
📍 Madrid