Overview
The Höpfler lab at the Institute for Genomic Regulation (CRG) is offering a postdoctoral position focused on RNA biology and gene regulation.
The role involves leading a project to develop sequencing methods that identify messenger RNA (mRNA) decay substrates and to decipher the mechanisms of degradation.
Responsibilities
Develop sequencing approaches to identify peptide-mediated mRNA decay (PMD) substrates
Perform bioinformatic data analysis and visualization of sequencing datasets
Identify and mechanistically characterize PMD candidate substrates
Present data at international conferences and prepare manuscripts
Lead and manage international collaborations
Actively participate in lab meetings and contribute to a culture of technical excellence and scientific curiosity
Qualifications
We are particularly interested in candidates with a hybrid wet?lab and bioinformatics background who have a track record in RNA biology or gene regulation.
Must Have
Bioinformatics experience in the analysis of (RNA) sequencing data
Experience with common laboratory techniques in cell and molecular biology
PhD degree (or expected to complete the degree before starting) in cell/molecular biology, bioinformatics, or a related field
Strong publication record commensurate with career stage
Ability to pursue research projects independently
Desirable
Experience with massively parallel reporter assays (MPRAs)




Experience exploring mRNA turnover on a transcriptome?wide scale
Background in RNA biology, translational control, or related areas
Languages
Fluency in written and spoken English
Computer Skills
Proficiency with data analysis software (R, Python)
Experience using high?performance computing clusters
Advanced MS Office experience
Competences
Curiosity and critical thinking
Rigor, organization, and autonomy
Strong analytical, interpersonal, and communication skills
Offer – Working Conditions
Contract duration: Technical and scientific activities contract (estimated duration 2 years)
Estimated annual gross salary: Salary will be commensurate with qualifications and consistent with our pay scales
Target start date: from October **** (flexible)
EEO Statement
We offer and promote a diverse and inclusive environment and welcome applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation or gender identity.
The CRG is committed to reconciling work and family life of its employees and offers extended vacation periods and the possibility to benefit from adaptable working hours.
Application Deadline
The position will remain open until it is covered.
Contact
Markus Höpfler
******
Additional information can be found on the lab website:
#J-*****-Ljbffr

📌 Postdoc In The Dynamics Of Protein Synthesis And Rna Decay Lab (Barcelona)
🏢 Centre For Genomic Regulation
📍 Barcelona