My client is a CRO that supports pharmaceutical development from early preclinical phases through late‑stage clinical research, supporting the development of the next generation of therapeutics.

The principal scientist will provide high‑level scientific and technical leadership across bioanalytical activities, with a focus on LC/MS/MS method development, validation and project management for NCEs, proteins, peptides, oligonucleotides and drug conjugates.

Key Responsibilities

Lead and oversee bioanalytical method development projects, particularly for NCEs, small molecules, peptides, and oligonucleotides.

Coordinate GLP/GCP‑compliant method development and validation (ICH) for quantifying drugs, metabolites, and biomarkers in biological matrices using LC‑MS/MS.

Provide scientific direction, troubleshooting, and interpretation for complex and high‑priority client projects.

Maintain transparent, client‑oriented communication with clients, ensuring scientific proposal writing, project scoping, and technical discussions and timely updates.





Support business development through generation of marketing material as well as presenting at key scientific conferences.

Qualifications

Extensive experience in bioanalytical LC‑MS/MS method development and validation.

Strong experience with proteins and peptides is highly valued.

Experience as a project leader coordinating and managing multiple projects simultaneously.

Solid understanding of international bioanalytical guidelines; experience working under GLP/GCP.

What Is Offered

Salary up to €60,000 DOE.

Opportunity to contribute to the continued success and growth of an expanding, high‑quality CRO.

Strong career progression opportunities to a management role outlined from day 1.

Access to cutting‑edge laboratory technology and modern analytical platforms.

A professional, diligent organisation with a human touch, strong values, and a commitment to excellence.

Seniority level Mid‑Senior level

Employment type Full‑time

Job function Science and Project Management

Industries Research Services

Location: Sant Just Desvern, Catalonia, Spain

📌 Bioanalytical Principal Scientist (Madrid)
🏢 Nexus Life Sciences
📍 Madrid