LOCATION: SWITZERLAND OR SPAIN

MAIN TASKS: Performance Management & KPIs

Define and implement a comprehensive R&D; performance framework, including KPIs, metrics, and dashboards across all functions;

Establish clear tracking of deliverables, milestones, timelines, cost, and quality indicators;

Enable transparency and fact-based decision-making through regular performance reporting to leadership;

Monitor portfolio execution performance and identify risks and mitigation actions.

Operational Excellence & Continuous Improvement

Lead structured diagnostics of R&D; processes (As-Is / To-Be) including value stream mapping, root cause analysis, and identification of inefficiencies;

Design and implement end-to-end process re-engineering initiatives to simplify workflows, reduce cycle times, and improve quality;

Drive standardization across functions while enabling flexibility for project-specific needs;

Drive continuous improvement initiatives across R&D; using Lean Six Sigma and other operational excellence methodologies;

Lead cross-functional optimization programs to enhance productivity, speed, and quality of development.

Process & Operating Model Optimization

Design, harmonize, and optimize end-to-end R&D; processes across CMC, Clinical, Regulatory, Device, Project Management and Medical Affairs;

Provide input and recommendations on R&D; operating models, governance structures, and ways of working;

Ensure alignment between general processes and local execution.

Tools & Digital Enablement

Assess and optimize R&D; tools and systems supporting planning, tracking, and execution;

Drive adoption of digital tools and data management solutions to enhance performance visibility and collaboration;

Ensure integration and consistency of tools across functions.

Change Management & Culture





Drive a culture of performance, accountability, and continuous improvement across R&D;

Support change management initiatives linked to transformation programs (e.g., ACE, Rejuvenate);

Build capabilities within teams in operational excellence methodologies.

QUALIFICATION PROFILE: Education & Languages

Advanced scientific degree in life science. Biotechnology is a plus;

Lean six sigma black belt (mandatory);

Project Management certification (a strong asset);

Hands on experience with compliance and quality systems. Literate / Gx certified is a plus;

Fluent in English (written, spoken), additional languages are an asset.

Professional Skills & Experience

Minimum 10+ years of experience in biopharma/biotech R&D;, including cross-functional exposure (CMC, Clinical, Regulatory, or PM);

Proven experience in operational excellence, performance management, or transformation roles within R&D; organizations;

Strong track record in implementing KPIs, dashboards, and performance governance frameworks;

Demonstrated experience in process optimization and end-to-end value stream improvement;

Experience with Lean Six Sigma methodologies and continuous improvement programs;

Solid understanding of drug development lifecycle and regulatory requirements;

Experience working in global, matrix organizations.

Personal Skills & Competencies

Strong analytical and problem-solving skills, with a data-driven mindset;

Ability to translate complex operational challenges into actionable improvement plans;

High level of ownership and results orientation;

Excellent stakeholder management and influencing skills across seniority levels;

Strong communication and facilitation skills;

Ability to work across functions and drive alignment in a matrix environment;

Change agent with the ability to drive transformation and cultural shift.

📌 Director R&D Operational Excellence & Performance (m/f/d) (Madrid)
🏢 Fresenius SE u0026 Co.
📍 Madrid