Call for expressions of interest for the submission of Marie Sklodowska Curie proposals in Redox... - [XN074]

Call for expressions of interest for the submission of Marie Sklodowska Curie proposals in Redox... - [XN074]

26 mar
|
Universitat Pompeu Fabra
|
Barcelona

26 mar

Universitat Pompeu Fabra

Barcelona

Oxidative stress constitutes the basis of physio-pathological situations such as neurodegenerative diseases and aging. However, reactive oxygen species such as hydrogen peroxide also exert signalling roles: they may activate antioxidant cascades, and endogenous increases of these species may even improve the overall fitness of the cell and trigger life span extension. Our lab uses the eukaryotic model system Schizosaccharomyces pombe to study the toxicity associated to oxygen-derived species, specifically protein oxidation and aggregation, and to describe the signalling processes controlled by oxidants. We have developed genetically-encoded fluorescent reporters to study in vivo fluctuations of hydrogen peroxide,

to unambiguously demonstrate the links between oxidant levels and cellular events, with the final goal of deciphering the molecular bases of processes such as mitochondrial metabolism, protein quality control and aging.



As a consequence of developing a multidisciplinary project, a solid background in Genetics, Cell Biology and Molecular Biology is a requirement to carry out this project; previous work with yeast, stress responses and protein quality control is not required, but will be a plus. Our group and the Department will also be involved in the candidate’s career development.



To obtain more information about the laboratory, about our research interests, and about our latest publications, please consult our group’s web page (). Elena Hidalgo will be delighted to sponsor 1 post-doctoral researcher in this call.

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https://www.kitempleo.es/empleo/17049143/call-for-expressions-interest-for-the-submission-marie-sklodowska-curie-proposals-redox-xn074-barcelona/?utm_source=html

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